Senolytics Target Senescent Cancer Cells for Death
D
Dr Joe Zundell PhD, cancer biologist, on Siim Land's podcast
General HealthMedical
Story of claim
Senolytics, like BCL2 inhibitors, target senescent pathways to induce cell death in cancer cells. This approach aims to exploit the senescent state of cancer cells to eliminate them.
- Goal: To induce cell death in cancer cells by targeting senescent pathways.
- Proof: Senolytics, by targeting senescent pathways, can induce death in senescent cancer cells.
- Nuances:
- Use of BCL2 inhibitors
- Targeting secretory factors like IL6
- Impact on Life: Potentially improves treatment outcomes for patients with late-stage tumors by targeting resistant cancer cells.
Investments
- Price:
- Time:
- Effort: High due to complexity in targeting diverse mechanisms
Risks
The complexity of diverse mechanisms in different cancer types may pose challenges.
Alternatives
- Traditional chemotherapy
- Radiation therapy
Get Started 🚀
- Consult with an oncologist about senolytic therapies.
- Research BCL2 inhibitors and their availability.
- Consider combination with other cancer treatments.
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