Rapamycin Extends Lifespan in Mice, Metformin Does Not

D

Dr. Peter Attia on The Tim Ferriss Show

Quotes From Source

“In the ITP, metformin did not succeed...”

Story of claim

Dr. Attia explains that rapamycin consistently extends lifespan in animal studies, unlike metformin, which only shows benefits when combined with rapamycin. The ITP program confirms these findings.

  • Goal: To explore effective longevity interventions.
  • Proof: Rapamycin consistently improves lifespan in mice; metformin does not unless combined with rapamycin.
  • Nuances:
    • Metformin has human data but lacks randomized studies.
    • Rapamycin was effective even when introduced late in life for mice.
  • Impact on Life: Could lead to significant breakthroughs in anti-aging research, potentially influencing future human studies.

Investments

  • Price: Research costs not specified
  • Time: Ongoing research; specific timeline not provided
  • Effort: Requires significant research and testing

Risks

Rapamycin's effects in humans are not fully understood; potential for unforeseen side effects.

Get Started 🚀

  • Review rapamycin studies in the ITP program
  • Consider implications for future human trials
  • Collaborate with researchers focusing on anti-aging

Brogevity AI can make mistakes. Check important info.

Reference Video