Optogenetics Controls Brain Cells with Light

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Peter Attia's podcast episode with Feng Zhang

Mental HealthMedical

Quotes From Source

We developed a technology called optogenetics...

Story of claim

Optogenetics uses light to study brain cell function, inserting a light-sensitive gene from algae into brain cells to control activity with blue or yellow light.

  • Goal: Feng seeks to use optogenetics to understand brain cell functions and connections.
  • Proof: Optogenetics offers precise control over brain cell activity using light-sensitive genes, enhancing brain research.
  • Nuances:
    • Uses genes from green algae to convert light into electrical current.
    • Allows control of specific neurons with targeted light.
  • Impact on Life: Enhances research capabilities in neuroscience, potentially leading to breakthroughs in understanding brain disorders.

Investments

  • Price:
  • Time: Requires extensive research and experimentation
  • Effort: High precision and technical complexity in gene insertion

Risks

Complexity in gene insertion; potential off-target effects.

Alternatives

  • Traditional electrophysiology
  • Chemical neuromodulation

Get Started 🚀

  • Learn about optogenetic tools and methods.
  • Access labs with optogenetic capabilities.
  • Study specific gene and light interactions.

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Reference Video