NMN Fails to Impact Epigenetic Clocks or DNA Repair
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Discussion on NAD+ and longevity featuring @WellnessMessiah
Anti-AgingTesting
Story of claim
NMN supplementation showed no effect on epigenetic clocks or DNA repair in mice, raising doubts about its efficacy in longevity interventions.
- Goal: To assess NMN's ability to influence epigenetic markers and improve DNA repair.
- Proof: NMN did not alter epigenetic clocks or enhance DNA repair mechanisms, suggesting limited impact on aging pathways.
- Nuances:
- Nicotinamide spike may inhibit sirtuins
- Single NAD cycle observed in cells
- Impact on Life: No significant changes in longevity markers were noted, indicating limited application for lifespan extension.
Investments
- Price: Estimation $50-$100 per month for NMN supplementation
- Time: Daily supplementation over several weeks
- Effort: Requires consistent supplementation routine
Risks
Potential for nicotinamide accumulation, inhibiting beneficial enzymes.
Get Started 🚀
- Consider alternative longevity strategies
- Consult with a healthcare professional before starting NMN
- Monitor for any changes in health markers over time
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