mTOR1 Activation Links to Macrocephaly and Depression

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Dr. Jon Berner's discussion on mTOR1 and depression, Aging-US series.

Mental HealthMedical

Quotes From Source

“Increased mTOR1 activation linked to macrocephaly and depression...”

Story of claim

Dr. Jon Berner links constitutive mTOR1 activation to macrocephaly and depression, highlighting a phenotypic variant affecting growth and mood regulation.

  • Goal: To explore the molecular basis of depression and physical growth abnormalities.
  • Proof: High mTOR1 activation affects entire body, influencing mood and growth.
  • Nuances:
    • Linked to P10 knockouts in rodents.
    • Affects the entire body, not just brain cells.
  • Impact on Life: Understanding these links may lead to novel treatments for depression and growth issues.

Investments

  • Price: Research-oriented; no direct cost for individuals.
  • Time: Ongoing research in this field.
  • Effort: Requires understanding of complex molecular biology.

Risks

Misinterpretation could lead to inappropriate medical interventions without further research.

Alternatives

  • Exploring genetic testing for mTOR-related conditions.

Get Started 🚀

  • Consult with geneticists if macrocephaly or depression is present.
  • Stay updated on mTOR research developments.

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Reference Video