Metformin and Rapamycin for Neurodegeneration Prevention

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Wise Athletes Podcast episode with Daniel Tawfik (GetHealthSpan Channel)

Anti-AgingMental HealthMedical

Quotes From Source

“Rapamycin and Metformin as molecules to be a prophylactic against Alzheimer's.”

Story of claim

Metformin and rapamycin are explored in animal models for preventing neurodegenerative diseases like Alzheimer's by targeting metabolic pathways involved in inflammation and cell growth.

  • Goal: Prevent neurodegeneration using metformin and rapamycin.
  • Proof: Metformin and rapamycin target metabolic pathways that could prevent the onset of neurodegenerative diseases by reducing inflammation and abnormal cell growth.
  • Nuances:
    • Metformin helps prevent cancer due to metabolic quirks of cancer cells.
    • Rapamycin is an immunosuppressant drug.
  • Impact on Life: Potentially delays onset of neurodegenerative diseases, improving quality of life with aging.

Investments

  • Price: $80-120 per month for medications
  • Time: Long-term commitment with periodic monitoring
  • Effort: Requires ongoing medical supervision and adherence to dosing schedule

Risks

Possible side effects include immune suppression from rapamycin. Regular monitoring is essential to manage risks.

Alternatives

  • Lifestyle modifications like diet and exercise for brain health
  • Other pharmacological agents under research for neuroprotection

Get Started 🚀

  • Consult with a healthcare professional about off-label use of metformin and rapamycin.
  • Monitor health markers regularly to track effectiveness.
  • Understand potential side effects and manage them with your doctor.
  • Join a support group or community for shared experiences.

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Reference Video