LC3 Redistribution Tracks Autophagy in Humans

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Dr. Guido Kroemer on Rhonda Patrick's podcast

Anti-AgingTesting

Quotes From Source

“LC3 redistributes from diffuse to punctate form in autophagy.”

Story of claim

Dr. Kroemer describes using LC3 redistribution in white blood cells as a method to detect autophagy, requiring advanced cytofluorometry technology.

  • Goal: To measure autophagy in humans via leukocytes.
  • Proof: LC3 redistribution indicates autophagy, visible through immunofluorescence.
  • Nuances:
    • Requires advanced cytofluorometry technology.
    • Standard devices measure fluorescence intensity, not distribution.
  • Impact on Life: Allows researchers to measure autophagy in humans, potentially advancing clinical research.

Investments

  • Price: Advanced technology may involve high costs.
  • Time: Research and technology development required.
  • Effort: Access to specialized equipment and expertise.

Risks

Technical complexity and cost may limit accessibility.

Alternatives

  • Standard autophagy assays using simpler equipment
  • Collaboration with specialized research facilities

Get Started 🚀

  • Access to a lab with cytofluorometry capabilities.
  • Training in advanced immunofluorescence techniques.
  • Collaboration with clinical researchers.

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