Ketamine Alters Brain Equilibrium via Anti-Inflammatory Effects

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Dr. Jon Berner's discussion in the Longevity & Aging Series, Aging-US, October 23, 2024.

Mental HealthMedical

Quotes From Source

Ketamine's effect is related to its central anti-inflammatory effects...

Story of claim

Dr. Jon Berner highlights ketamine's central anti-inflammatory effects, altering brain microglial populations, significantly benefiting psychiatric patients.

  • Goal: Improving psychiatric treatment outcomes using ketamine.
  • Proof: Ketamine changes microglial distributions, with a 55% response rate in treatment-resistant depression.
  • Nuances:
    • Influences type one microa and m2c microglia.
    • IL 10 and corticosteroids are key promoters.
  • Impact on Life: Ketamine can rapidly alleviate symptoms in treatment-resistant depression, potentially improving overall mental health.

Investments

  • Price: $400-800 per treatment session, depending on location.
  • Time: Initial effects seen after a few sessions.
  • Effort: Requires multiple sessions and monitoring for side effects.

Risks

Potential for dissociative experiences and dependency. Monitoring for psychological side effects is crucial.

Alternatives

  • Electroconvulsive therapy (ECT) for severe depression
  • Oral antidepressants for less severe cases

Get Started 🚀

  • Consult with a psychiatrist specializing in ketamine treatments.
  • Undergo an initial assessment to determine suitability.
  • Plan for multiple sessions to evaluate effectiveness.
  • Monitor and report any psychological changes.

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