Ketamine Alters Brain Equilibrium via Anti-Inflammatory Effects
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Dr. Jon Berner's discussion in the Longevity & Aging Series, Aging-US, October 23, 2024.
Mental HealthMedical
Story of claim
Dr. Jon Berner highlights ketamine's central anti-inflammatory effects, altering brain microglial populations, significantly benefiting psychiatric patients.
- Goal: Improving psychiatric treatment outcomes using ketamine.
- Proof: Ketamine changes microglial distributions, with a 55% response rate in treatment-resistant depression.
- Nuances:
- Influences type one microa and m2c microglia.
- IL 10 and corticosteroids are key promoters.
- Impact on Life: Ketamine can rapidly alleviate symptoms in treatment-resistant depression, potentially improving overall mental health.
Investments
- Price: $400-800 per treatment session, depending on location.
- Time: Initial effects seen after a few sessions.
- Effort: Requires multiple sessions and monitoring for side effects.
Risks
Potential for dissociative experiences and dependency. Monitoring for psychological side effects is crucial.
Alternatives
- Electroconvulsive therapy (ECT) for severe depression
- Oral antidepressants for less severe cases
Get Started 🚀
- Consult with a psychiatrist specializing in ketamine treatments.
- Undergo an initial assessment to determine suitability.
- Plan for multiple sessions to evaluate effectiveness.
- Monitor and report any psychological changes.
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