Intermittent Fasting Extends Mice Lifespan

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Dr. Guido Kroemer on Rhonda Patrick's podcast

Anti-AgingLifestyle

Quotes From Source

“Intermittent fasting and caloric restriction both extend lifespan.”

Story of claim

Intermittent fasting in mice shows similar longevity benefits as caloric restriction, offering a simpler and potentially more sustainable dietary intervention.

  • Goal: Compare effects of intermittent fasting and caloric restriction on lifespan.
  • Proof: Mice adapt to intermittent fasting by showing similar lifespan extension without the need for constant caloric restriction.
  • Nuances:
    • Mice adapt to stress, showing smaller weight oscillations over time.
    • Intermittent fasting results in same weight as normally fed mice.
  • Impact on Life: Could provide a viable alternative to caloric restriction for longevity, with less daily dietary stress.

Investments

  • Price: No financial cost, but potential lifestyle adjustments
  • Time: Intermittent fasting is a daily routine commitment
  • Effort: Requires adjustment to new eating patterns and potential initial hunger.

Risks

Potential for nutritional deficiencies if not properly managed, especially in humans.

Alternatives

  • Caloric restriction for those able to sustain it
  • Time-restricted eating for a more flexible schedule

Get Started 🚀

  • Start with a 16:8 fasting schedule, fasting for 16 hours and eating within an 8-hour window.
  • Gradually increase fasting duration as comfort allows.
  • Ensure meals are balanced and nutrient-rich during eating windows.

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Reference Video