Hydroxycitric and Spermidine Induce Autophagy in Mice

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Dr. Guido Kroemer on Rhonda Patrick's podcast.

Anti-AgingSupplements

Quotes From Source

“Supplements induce autophagy with a normal diet in mice.”

Story of claim

In mice, hydroxycitric and spermidine supplements induce autophagy without caloric restriction, mimicking fasting benefits. This approach is promising for anti-aging effects.

  • Goal: Induce autophagy without caloric restriction.
  • Proof: Supplements mimic fasting benefits by inducing autophagy in mice, as shown in studies.
  • Nuances:
    • Spermidine may depend on autophagy for reducing weight gain.
    • No clinical studies in humans on supplement-induced autophagy.
  • Impact on Life: Potential for anti-aging benefits and weight management in individuals.

Investments

  • Price: Estimated $30-60 per month for supplements
  • Time: Daily supplementation
  • Effort: Requires regular intake and lifestyle consistency

Risks

Lack of human studies on long-term effects. Potential for unknown side effects.

Alternatives

  • Traditional fasting and caloric restriction
  • Exploring other autophagy-inducing supplements

Get Started 🚀

  • Purchase hydroxycitric and spermidine supplements.
  • Incorporate supplements into your daily routine.
  • Monitor for any changes in weight or health.
  • Consult a healthcare provider if unsure about supplement use.

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Reference Video