Metformin and Berberine Have No Lifespan Benefit

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Dr. Andrew Huberman's YouTube discussion

Anti-AgingSupplements

Quotes From Source

“Berberine gives me brutal headaches.”

Story of claim

Dr. Huberman avoids metformin and berberine for lifespan due to lack of evidence and personal side effects. Berberine causes headaches; metformin does not extend lifespan significantly.

  • Goal: Evaluate effectiveness and personal impact of longevity supplements.
  • Proof: Insufficient data to support lifespan extension with metformin; berberine causes personal discomfort.
  • Nuances:
    • Berberine causes brutal headaches for Dr. Huberman
    • Metformin affects mTOR pathways, linked to cell growth
  • Impact on Life: Avoids discomfort and unproven benefits by not using these supplements.

Investments

  • Price: $0 for not using supplements
  • Time: No time investment required
  • Effort: No effort needed in consuming supplements

Risks

Berberine may induce headaches; metformin lacks substantial evidence for lifespan increase.

Alternatives

  • Focus on lifestyle changes such as diet and exercise for longevity

Get Started 🚀

  • Consider lifestyle changes like exercise and balanced diet for longevity
  • Consult a physician before considering longevity supplements

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Reference Video