Debated Potential of GLP-1 Agonists in Aging
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Matt Kaeberlein's Optispan Podcast episode on October 22, 2024
Anti-AgingMedical
Story of claim
Matt discusses the debated effect of GLP-1 agonists on biological aging, questioning if it's linked to calorie restriction or another mechanism.
- Goal: Explore GLP-1 agonists as a means to slow biological aging.
- Proof: Calorie restriction has been linked to slowed biological aging, and GLP-1 agonists may mimic this effect.
- Nuances:
- Metabolic dysfunction accelerates aging.
- Calorie restriction may mitigate metabolic dysfunction.
- Efficacy in normal weight individuals is uncertain.
- Impact on Life: May offer new avenues for slowing biological aging, with implications for longevity and health span.
Investments
- Price: $1200-1500 per year for GLP-1 agonists
- Time: Long-term commitment
- Effort: Requires adherence to treatment and monitoring
Risks
Uncertain effects in normal weight individuals; potential side effects.
Alternatives
- Dietary interventions focusing on calorie restriction
- Exercise programs targeting metabolic health
Get Started 🚀
- Discuss the potential use of GLP-1 agonists with a healthcare provider.
- Consider dietary changes that mimic calorie restriction.
- Regularly monitor metabolic health indicators.
- Evaluate the benefits and risks in consultation with a professional.
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