Gene Editing in China for HIV Immunity Sparks Debate

P

Peter Attia MD, referencing a 2018 gene editing case in China

ImmunityGeneral HealthMedicalContent

Quotes From Source

“A scientist edited embryos to make children immune to HIV.”

Story of claim

In 2018, a Chinese scientist edited embryos to grant HIV immunity, causing global ethical debates due to lack of medical necessity and incomplete editing leading to mosaicism.

  • Goal: To render children immune to HIV through gene editing.
  • Proof: The CCR5 mutation, naturally found in some individuals, was edited to prevent HIV infection, but resulted in mosaicism.
  • Nuances:
    • The case occurred in 2018.
    • The scientist edited the CCR5 gene.
    • The mutation is naturally present in a small percentage of the population.
    • The editing resulted in mosaicism in the embryos.
    • Embryos were implanted, leading to the birth of two girls.
  • Impact on Life: The case highlighted ethical concerns and sparked global debate, potentially impacting future regulations and scientific approaches.

Investments

  • Price: Estimated significant costs for research and implementation
  • Time: Several years of research and development
  • Effort: High scientific and ethical challenges

Risks

Potential health risks due to mosaicism and ethical concerns over unauthorized gene editing.

Alternatives

  • Pre-implantation genetic testing
  • HIV preventive measures like PrEP

Get Started 🚀

  • Understand the basics of gene editing and CCR5 mutation.
  • Review ethical guidelines and legal regulations.
  • Consider the implications of unauthorized scientific experiments.
  • Stay updated with scientific advancements in gene editing.

Brogevity AI can make mistakes. Check important info.

Reference Video