Gene Editing in China for HIV Immunity Sparks Debate
P
Peter Attia MD, referencing a 2018 gene editing case in China
ImmunityGeneral HealthMedicalContent
Story of claim
In 2018, a Chinese scientist edited embryos to grant HIV immunity, causing global ethical debates due to lack of medical necessity and incomplete editing leading to mosaicism.
- Goal: To render children immune to HIV through gene editing.
- Proof: The CCR5 mutation, naturally found in some individuals, was edited to prevent HIV infection, but resulted in mosaicism.
- Nuances:
- The case occurred in 2018.
- The scientist edited the CCR5 gene.
- The mutation is naturally present in a small percentage of the population.
- The editing resulted in mosaicism in the embryos.
- Embryos were implanted, leading to the birth of two girls.
- Impact on Life: The case highlighted ethical concerns and sparked global debate, potentially impacting future regulations and scientific approaches.
Investments
- Price: Estimated significant costs for research and implementation
- Time: Several years of research and development
- Effort: High scientific and ethical challenges
Risks
Potential health risks due to mosaicism and ethical concerns over unauthorized gene editing.
Alternatives
- Pre-implantation genetic testing
- HIV preventive measures like PrEP
Get Started 🚀
- Understand the basics of gene editing and CCR5 mutation.
- Review ethical guidelines and legal regulations.
- Consider the implications of unauthorized scientific experiments.
- Stay updated with scientific advancements in gene editing.
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