Story of claim

Modulating gene expression to produce fetal hemoglobin can alleviate sickle cell symptoms. This involves simple gene modification techniques.

• Goal: Enable fetal hemoglobin production to reduce sickle cell symptoms.
• Proof: Gene editing modulates gene expression to activate fetal hemoglobin, reducing symptoms.
• Nuances:
  • Focus on gene expression rather than fixing mutation
  • Symptoms reduce when fetal hemoglobin is expressed
• Impact on Life: Potential reduction in sickle cell disease symptoms.