CRISPR Restores Vision in Genetic Eye Conditions

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Peter Attia MD podcast episode with Feng Zhang

Eye HealthMedical

Quotes From Source

Viral vector delivers Cas9 and guide RNA intraocularly...

Story of claim

Feng Zhang discusses using CRISPR for ocular gene therapy to treat genetic eye conditions, improving patients' light sensitivity and vision.

  • Goal: To restore vision in patients with genetic eye conditions using CRISPR.
  • Proof: CRISPR offers precise genetic corrections, partially restoring vision in degenerating retinas.
  • Nuances:
    • LCA10 and LCA2 are genetic eye conditions targeted by CRISPR
    • Gene therapy can partially restore vision in degenerating retinas
  • Impact on Life: Potentially restores some vision, improving quality of life for affected individuals.

Investments

  • Price: Not specified
  • Time: Ongoing research and clinical trials
  • Effort: High due to precision required in ocular gene editing

Risks

Potential for unintended genetic changes.

Get Started 🚀

  • Develop CRISPR-based therapies for ocular conditions
  • Use viral vectors for intraocular delivery
  • Monitor patient outcomes for improved vision

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Reference Video