CRISPR Silences Genes for Therapeutic Benefits

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Peter Attia MD's podcast with Feng Zhang on October 28, 2024

General HealthContent

Quotes From Source

“CRISPR is a natural nuclease...”

Story of claim

CRISPR can silence overexpressed genes causing diseases, offering a targeted therapeutic strategy to reduce or eliminate symptoms.

  • Goal: Use CRISPR to silence overexpressed genes causing disease to improve patient outcomes.
  • Proof: Silencing genes can mitigate diseases caused by gene overexpression, potentially improving patient outcomes.
  • Nuances:
    • Gene silencing provides a targeted approach for diseases caused by gene overexpression.
    • Maria Jason and Jim Haber studied DNA repair processes.
  • Impact on Life: Improves patient outcomes and quality of life by reducing symptoms of diseases caused by gene overexpression.

Investments

  • Price: Not explicitly mentioned.
  • Time: Dependent on the specific gene and disease.
  • Effort: Requires precise targeting and validation.

Risks

Unintended gene silencing and ethical concerns.

Get Started 🚀

  • Identify genes responsible for disease overexpression.
  • Apply CRISPR to silence these genes.

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Reference Video