APOE2 Genotype Linked to Longevity in Centenarians

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Peter Attia & Nir Barzilai YouTube video

Quotes From Source

“Centenarians are more likely to have APOE2 than non-centenarians.”

Story of claim

APOE2 is a protective longevity genotype more common in centenarians. Despite being linked to diseases, it's the most validated longevity genotype.

  • Goal: Understand genetic factors contributing to longevity.
  • Proof: APOE2 is frequently found in centenarians, suggesting its role in promoting longevity.
  • Nuances:
    • APOE2 is also associated with some diseases.
    • Studies might have bias due to exclusion of dementia patients.
  • Impact on Life: Potentially enables a longer, healthier life by delaying age-related diseases.

Investments

  • Price: Genetic testing costs vary; typically $100-200
  • Time: Genetic testing takes a few weeks
  • Effort: Minimal effort for testing; lifestyle changes may follow

Risks

Potential emotional impact of genetic test results indicating predisposition to diseases.

Alternatives

  • Focus on lifestyle factors like diet and exercise for longevity

Get Started 🚀

  • Consult with a genetic counselor about testing for APOE2.
  • Order a genetic test kit online or through a healthcare provider.
  • Receive and interpret results with professional guidance.
  • Implement lifestyle changes based on genetic insights.

Brogevity AI can make mistakes. Check important info.

Reference Video